Researchers have found that pancreatic cancer can be split into four unique types, a discovery that could be used to improve treatments for the disease, according to a study published in Nature. The four subgroups were classified as having DNA that was stable, locally rearranged, scattered and unstable. The international team of scientists, including Cancer Research UK researchers, found that these four types were created when large chunks of DNA are shuffled around. The team also identified the genes that could be damaged in this way.
Link to the research: Waddell, N. et al, ‘Whole Genomes Redefine the Mutational Landscape of Pancreatic Cancer’. Nature, 2015.