Efficacy of recreational football on bone health, body composition, and physical functioning in men with prostate cancer undergoing androgen deprivation therapy

Uth, J. et al. (2015) Osteoporosis International. First online: 16 November 

Image source: NHS PhotoLibrary

Summary from ScienceDirect

Men with prostate cancer run the risk of brittle bones as a side-effect of their treatment. But one hour’s soccer training a few times a week counters many of the negative effects of the treatment, according to University of Copenhagen scientists.


ADT is a mainstay in PCa management. Side effects include decreased bone and muscle strength and increased fracture rates. The purpose of the present study was to evaluate the effects of 32 weeks of football training on BMD, bone turnover markers (BTMs), body composition, and physical functioning in men with PCa undergoing ADT.


Men receiving ADT >6 months (n = 57) were randomly allocated to a football training group (FTG) (n = 29) practising 2–3 times per week for 45–60 min or to a standard care control group (CON) (n = 28) for 32 weeks. Outcomes were total hip, femoral shaft, femoral neck and lumbar spine (L2-L4) BMD and systemic BTMs (procollagen type 1 amino-terminal propeptide, osteocalcin, C-terminal telopeptide of type 1 collagen). Additionally, physical functioning (postural balance, jump height, repeated chair rise, stair climbing) was evaluated.


Thirty-two-week follow-up measures were obtained for FTG (n = 21) and for CON (n = 20), respectively. Analysis of mean changes from baseline to 32 weeks showed significant differences between FTG and CON in right (0.015 g/cm2) and left (0.017 g/cm2) total hip and in right (0.018 g/cm2) and left (0.024 g/cm2) femoral shaft BMD, jump height (1.7 cm) and stair climbing (−0.21 s) all in favour of FTG (p < 0.05). No other significant between-group differences were observed.


Compared to standard care, 32 weeks of football training improved BMD at clinically important femoral sites and parameters of physical functioning in men undergoing ADT for PCa.

View abstract from Springer


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