The study in over 5,500 women found that younger patients and those who had taken hormone replacement therapy (HRT) were less likely to adhere to their medicine | ScienceDaily
Around 20% of breast cancer patients do not complete prescribed endocrine therapy, researchers report at the ESMO Asia 2016 Congress in Singapore.
The study included 5,544 women with ER positive breast cancer who collected at least one prescription of aromatase inhibitors or tamoxifen and had five years of follow up data. Women were identified and prescription information was obtained from the regional registers of Uppsala-Örebro, Stockholm-Gotland, and Northern Sweden which cover around 60% of the Swedish population. The data was linked to Swedish national registers with information about factors which could influence adherence. Adherence was calculated from the drugs dispensed — patients were classified as non-adherent if they received less than 80% of the drugs needed over five years.
During the five years, 20% of the women became non-adherent. In the multivariable analysis the strongest independent predictors of non-adherence were younger age, previous use of HRT, marital status, and socioeconomic status (measured by type of employment).
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