Mustian, K.M. et al. JAMA Oncology | Published online: 2 March 2017
Question: Which of the 4 most commonly recommended treatments for cancer-related-fatigue—exercise, psychological, the combination of exercise and psychological, and pharmaceutical—is the most effective?
Findings: This meta-analysis of 113 unique studies (11 525 unique participants) found that exercise and psychological interventions and the combination of both reduce cancer-related fatigue during and after cancer treatment. Reduction was not due to time, attention, or education. In contrast, pharmaceutical interventions do not improve cancer-related fatigue to the same magnitude.
Meaning: Clinicians should prescribe exercise and/or psychological interventions as first-line treatments for cancer-related fatigue.
Read the abstract here