Earlier discovery of cancer and greater precision in the treatment process are the objectives of a new method recently developed. | ScienceDaily
Screening of at-risk groups for certain types of cancer, leading to earlier diagnosis, is being described as an area with major potential, both with regard to saving lives and saving money within healthcare. No tissue samples are needed for the method, and the tumor does not even need to be located. Investments are now being made to roll out this innovation across healthcare and broaden the scope of the research in this field.
The technique was created based on the fact that people with cancer also have DNA from tumor cells circulating in the blood, molecules that can be discovered in a regular blood sample long before the tumor is visible via imaging such as tomography, MRI, X-ray and ultrasound.
The researchers have now increased the sensitivity of detecting tumor DNA in blood thousand-fold by eliminating the background noise from the measurements using “DNA barcoding.”
Full story at ScienceDaily
Link to the research: Anders Ståhlberg, et al. Simple multiplexed PCR-based barcoding of DNA for ultrasensitive mutation detection by next-generation sequencing. Nature Protocols, 2017; 12 (4): 664