Concern over diagnostic variability for melanoma

Diagnoses spanning moderately dysplastic nevi to early stage invasive melanoma were neither reproducible nor accurate, according to the results of a large study of pathologists in the US.

Authors of the study, published by The BMJ, have called for efforts to improve clinical practice such as using a standardised classification system, acknowledging uncertainty in pathology reports, and developing tools such as molecular markers to support pathologists’ visual assessments. They also urged doctors to share with their patients that the practice of medicine can be inherently uncertain.

Full story via OnMedica

Link to the research: Elmore JG, et al. Pathologists’ diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility study. BMJ 2017; 357: j2813

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