Aspirin: a cure for bowel cancer?

University of Edinburgh |  June 2018 | Aspirin’s anti-cancer effects revealed

Researchers at the University of Edinburgh have discovered aspirin blocks a key process linked to tumour formation. Although aspirin  is recognised for its ability to reduce an individual’s risk of developing colon cancer-if taken regularly- its tumour fighting properties have been little understood. The team looked at the impact of taking aspirin to fight bowel cancer; focusing on a structure found inside cells called the nucleolus. They tested aspirin tumour biopsies removed from patients with colon cancer, and cells grown in the lab. Their research discovered that aspirin blocks TIF-IA a key molecule essential to the functioning of the nucleolus (via University of Edinburgh).
pharmacy-3087596_1920

Full press release from University of Edinburgh here 

The full article is available to read from Nucleic Acids Research

Chen, J. et al |2018|  Identification of a novel TIF-IA–NF-κB nucleolar stress response pathway| Nucleic Acids Research| gky455| https://doi.org/10.1093/nar/gky455

In the media:

BBC News Aspirin ‘helps block tumour formation’

 

 

 

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s